Sarah A. Reed
Associate Professor- Muscle Biology & Equine Science
Phone: (860) 486-8452
Office: George White Bldg., Room 203
Lab: George White Bldg., Room 206
Lab Phone: (860) 486-8457
- Ph.D. (Animal Molecular and Cellular Biology), University of Florida, 2009
- MD (Animal Science), University of Florida, 2006
- B.S. (Equine Science), Delaware Valley College, 2003
Dr. Reed pursued post doctoral training in muscle biology in the Department of Physical Therapy at the University of Florida and joined the faculty of the Department of Animal Science at UConn in 2011.
Area of Interest
- Effects of poor maternal nutrition on offspring growth and development, specifically muscle growth and development
- Physiology of exercise deconditioning and reconditioning in horses
- Impacts of inflammation and oxidative stress on muscle growth
- Muscle growth and development, including satellite cell function
Awards and Accomplishments
- UConn CETL Innovative Teaching Award, 2020
- UCAHNRA Excellence in Teaching Award, 2017
- CAHNR Donald M. Kinsman Award for Excellence in Teaching, 2015
- Northeast ASAS/ADSA Young Teacher Award, 2014
In the News
Recent Publications (Selected)
Gauvin MC, Pillai SM, Reed SA, Stevens JR, Hoffman ML, Jones AK, Zinn SA, Govoni KE. Poor maternal nutrition during gestation in sheep alters prenatal muscle growth and development in offspring. J Anim Sci. 2020 98(1). doi: 10.1093/jas/skz388
Martin D.E., A.K. Jones, S.M. Pillai, M.L. Hoffman, K.K. McFadden, S.A. Zinn, K.E. Govoni, and S.A. Reed. Maternal restricted- and over-feeding during gestation result in distinct lipid and amino acid metabolite profiles in the longissimus muscle of the offspring. Front Physiol. 2019. 10:515. doi: 10.3389/fphys.2019.00515
Govoni K.E., S.A. Reed, and S.A. Zinn. Poor maternal nutrition during gestation: Effects on offspring whole body and tissue-specific metabolism in livestock species. J Anim Sci. 2019. pii: skz157. doi: 10.1093/jas/skz157
Jones, A.K., R.E. Gately, T.D. Kellogg, S.A. Zinn, K.E. Govoni, and S.A. Reed. Evaluation of the Nova Vet Meter for sheep-side monitoring of beta-hydroxybutyric acid (BHBA) and description of ewe BHBA during late gestation in three flocks from the Northeastern U.S. Res Vet Sci. 2018. doi:10.1016.j.rvsc.2018.05.002
Jones, A.K., M.L. Hoffman, S.M. Pillai, K.K. McFadden, K.E. Govoni, S.A. Zinn, and S.A. Reed. Gestational restricted- and over-feeding promote maternal and offspring inflammatory responses that are distinct and dependent on diet in sheep. Biol Reprod. 2018. 98:184-196. doi:10.1093/biolre/iox174
Jones, A. K., & Reed, S. A. (2017). Benefits of ultrasound scanning during gestation in the small ruminant. 149, 163-171. 10.1016/j.smallrumres.2017.02.008
Pillai, S. M., Jones, A. K., Hoffman, M. L., McFadden, K. K., Reed, S. A., Zinn, S., & Govoni, K. (2017). Fetal and organ development at gestational days 45, 90, 135 and at birth of lambs exposed to under- or over-nutrition during gestation. 1, 16-25. 10.2527/tas2016.0002
Hoffman, M. L., Reed, S. A., Pillai, S. M., Jones, A. K., McFadden, K. K., Zinn, S., & Govoni, K. (2017). The effects of poor maternal nutrition during gestation on offspring postnatal growth and metabolism. 94, 3093-3099. 10.2527/jas.2016-1229
Jones, A. K., Gately, R. E., McFadden, K. K., Hoffman, M. L., Pillai, S. M., Zinn, S., Govoni, K., & Reed, S. A. (2017). Ultrasound during mid-gestation: Agreement with physical foetal and placental measurements and use in predicting gestational age in sheep. 10.1111/rda.12961
Hoffman, M. L., Peck, K. N., Wegrzyn, J., Reed, S. A., Zinn, S., & Govoni, K. (2016). Poor maternal nutrition during gestation alters the expression of genes i
nvolved in muscle development and metabolism in lambs. 94(7), 3093-9. 10.2527/jas.2016-0570
Raja JS, Hoffman ML, Govoni KE, Zinn SA, Reed SA
. Restricted maternal nutrition alters myogenic regulatory factor expression in satellite cells of ovine offspring. Animal. 2016 Feb 9:1-4.
Jones AK, Gately RE, McFadden KK, Zinn SA, Govoni KE, Reed SA.
Transabdominal ultrasound for detection of pregnancy, fetal and placental landmarks, and fetal age before Day 45 of gestation in the sheep. Theriogenology. 2016 Mar 15;85(5):939-45.e1. doi: 10.1016/j.theriogenology.2015.11.002.
LaVigne EK, Jones AK, Londoño AS, Schauer AS, Patterson DF, Nadeau JA, Reed SA
. Muscle growth in young horses: Effects of age, cytokines, and growth factors. J Anim Sci. 2015 Dec;93(12):5672-80. doi: 10.2527/jas.2015-9634.
. SafeAssign as a tool for student identification of potential plagiarism. Natural Sciences Education. 2015 July; 44:95-100
, LaVigne EK, Jones AK, Patterson DF, Schauer AL. HORSE SPECIES SYMPOSIUM: The aging horse: Effects of inflammation on muscle satellite cells. J Anim Sci. 2015 Mar;93(3):862-70.
, Johnson SE. Expression of scleraxis and tenascin C in equine adipose and umbilical cord blood derived stem cells is dependent upon substrata and FGF supplementation. Cytotechnology. 2014 Jan;66(1):27-35. doi: 10.1007/s10616-012-9533-3. Epub 2013 Jan 9.
, Raja JS, Hoffman ML, Zinn SA, Govoni KE. Poor maternal nutrition inhibits muscle development in ovine offspring. J Anim Sci Biotechnol. 2014 Sep 5;5(1):43. doi: 10.1186/2049-1891-5-43.
Leahy ER. Growth and Development Symposium: Stem cell therapy in equine tendon injury. J Anim Sci. 2013 Jan;91(1):59-65. doi: 10.2527/jas.2012-5736. Epub 2012 Oct 16. Invited Review.
Johnson SE. Refinement of culture conditions for maintenance of undifferentiated equine umbilical cord blood stem cells. Journal of equine veterinary science. 2012 June; 32(6):360-366.
, Sandesara PB, Senf SM, Judge AR. Inhibition of FoxO transcriptional activity prevents muscle fiber atrophy during cachexia and induces hypertrophy. FASEB J. 2012 Mar;26(3):987-1000. doi: 10.1096/fj.11-189977. Epub 2011 Nov 18.
Senf SM, Sandesara PB, Reed SA
, Judge AR. p300 Acetyltransferase activity differentially regulates the localization and activity of the FOXO homologues in skeletal muscle. Am J Physiol Cell Physiol. 2011 Jun;300(6):C1490-501. doi: 10.1152/ajpcell.00255.2010. Epub 2011 Mar 9.
, Senf SM, Cornwell EW, Kandarian SC, Judge AR. Inhibition of IkappaB kinase alpha (IKKα) or IKKbeta (IKKβ) plus forkhead box O (Foxo) abolishes skeletal muscle atrophy. Biochem Biophys Res Commun. 2011 Feb 18;405(3):491-6. doi: 10.1016/j.bbrc.2011.01.059.
Li J, Reed SA
, Johnson SE. Hepatocyte growth factor (HGF) signals through SHP2 to regulate primary mouse myoblast proliferation. Exp Cell Res. 2009 Aug 1;315(13):2284-92. doi: 10.1016/j.yexcr.2009.04.011.
, Johnson SE. Equine umbilical cord blood contains a population of stem cells that express Oct4 and differentiate into mesodermal and endodermal cell types. J Cell Physiol. 2008 May;215(2):329-36.
, Ouellette SE, Liu X, Allen RE, Johnson SE. E2F5 and LEK1 translocation to the nucleus is an early event demarcating myoblast quiescence. J Cell Biochem. 2007 Aug 15;101(6):1394-408.
Hobbies/ Non-Academic Interests
- Horseback Riding