Phone: (860) 486-1065
Office: George White Bldg., Room 201
Research in reproductive endocrinology is conducted in the laboratory of Robert A. Milvae. The primary area of interest is the investigation of the mechanisms involved in the regulation of bovine corpus luteum functions. The biology of the biosynthesis of progesterone is examined via a variety of approaches ranging from whole animal studies to molecular biology. The mechanisms by which local intraovarian compounds affect luteal function have been recently examined. Our current research results suggest that endothelins play an important role in luteolysis.
|ANSC 2699||Independent Study: Undergraduate Research|
|ANSC 2699||Independent Study: California Field Studies in Veterinary Medicine and the Race Horse Industry|
|ANSC 2699||Independent Study: Strategies for Enhancing Freshmen Success|
|ANSC 3122||Reproductive Physiology|
|ANSC 3272||Laboratory Animal Science|
|ANSC 3691||Professional Internship|
|ANSC 5692||Graduate Research|
Milvae, R., "Strategic Partnerships: Collaboration with The Race Horse Industry", National Academic Summit. (June 18, 2012).
Rhinehart JD, Starbuck-Clemmer MJ, Flores JA, Milvae RA, Poole DH, Inskeep EK. 2009. Low peripheral progesterone and late embnryonic/early fetal loss in suckled beef cows and lactating dairy cows. Theriogenology 71: 480-490.
Christopher S. Keator, David T. Schreiber, Thomas A. Hoagland, John A. McCracken, and Robert A. Milvae (2008). Intrauterine infusion of BQ-610, an endothelin type A receptor antagonist, delays luteolysis in dairy heifers 34: (in press).
Zhang B, ZhangH, Milvae RA, Keator C, Moses MA, Tsang PCW. 2005. Tissue inhibitor of metalloproteinases and its regulation by tumor necrosis factor in the bovine corpus luteum. Biol Reprod 72: Suppl 222.
Ricketts BF, Tsang PCW, Milvae RA, Keator CS, McCracken JA. 2005. Dynamic in vivo changes in protein levels of TIMP-1 and MMP-2 and -9 in the ovine corpus luteum after luteolytic pulses of PGF-2a. Biol Reprod 72: Suppl 547.
Keator CS, Schreiber DT, Milvae RA, McCracken JA. 2005. Nitric oxide alters progesterone secretion rate and blood flow in vivo and luteal cell production of progesterone in sheep. Biol Reprod 72: Suppl 618.
Towle, T.A., Tsang, P.C.W., Milvae, R.A., Newbury, M.K., McCracken, J.A. 2002. Dynamic in vivo changes in tissue inhibitors of metalloproteinases 1 and 2, and matrix metalloproteinases 2 and 9, during prostaglandin F-2a induced luteolysis in sheep. Biol Reprod 66:1515-1521.
Townson, D.H., Tsang, P.C.W., Butler, W.R., Frajblat, L.C., Johnson, C.J., Milvae, R.A., Niksic, G.M., Pate, J.L. 2002. Relationship of fertility to ovarian follicular waves before breeding in dairy cows. J Anim Sci 80:1053-1058.
Hinckley, S.T., Milvae, R.A. 2001. Endothelin-1 mediates prostaglandin induced luteal regression in the ewe. Biol Reprod 64:1619-1623.